Prescribers remain cautious about substituting generic drugs for narrow therapeutic index (NTI) medications like warfarin and levothyroxine due to risks of instability. While the FDA affirms generic safety, real-world data shows prescribers prioritize patient stability, leading to state-level restrictions and ongoing debate over substitution practices.
Nitrosamine contamination has triggered over 500 FDA recalls since 2018, affecting generics like metformin, ARBs, and antidepressants. Learn how these carcinogens form, which drugs are impacted, and what regulators and manufacturers are doing to fix it.
Therapeutic Drug Monitoring (TDM) is critical for patients taking generic narrow therapeutic index (NTI) drugs, where small changes in blood levels can cause serious harm. Learn when and why TDM saves lives.