Tag: clozapine

Clozapine and Smoking: How CYP1A2 Induction Affects Dose Requirements

Clozapine and Smoking: How CYP1A2 Induction Affects Dose Requirements

Smoking dramatically increases how fast clozapine is broken down in the body, requiring higher doses. Quitting smoking can cause dangerous drug buildup. Learn how to safely adjust doses and monitor levels to avoid serious side effects.

Parkinson’s Disease and Antipsychotics: How Medications Can Worsen Motor Symptoms

Parkinson’s Disease and Antipsychotics: How Medications Can Worsen Motor Symptoms

Antipsychotics can worsen Parkinson’s motor symptoms by blocking dopamine. Clozapine and quetiapine are safer options, but many drugs like haloperidol and risperidone are dangerous. Non-drug strategies often work first.